Please Note: This article is written for users of the following Microsoft Excel versions: 2007, 2010, 2013, 2016, 2019, and Excel in Office 365. If you are using an earlier version (Excel 2003 or earlier), this tip may not work for you. For a version of this tip written specifically for earlier versions of Excel, click here: How Excel Treats Disk Files.
Over the years Excel has used several different file extensions to denote that the file is, indeed, native to Excel:
If you use the Open dialog box to open any type of file besides these three, Excel will dutifully attempt to translate the information in that file into a meaningful format. For instance, if you attempt to open a file that contains nothing but text, Excel will read the information and place it in an otherwise blank workbook.
Excel can read files created by several other types of programs. The types of files you can open depend on your version of Excel. If there is any confusion as to how Excel should translate the file, it will ask you to select the type of translation to use.
When you load a file created by another program into Excel, you should understand that you might lose some formatting that is unique to that particular program. Rest assured, however, that Excel will do its absolute best to faithfully translate and load the file as you requested.
ExcelTips is your source for cost-effective Microsoft Excel training. This tip (12743) applies to Microsoft Excel 2007, 2010, 2013, 2016, 2019, and Excel in Office 365. You can find a version of this tip for the older menu interface of Excel here: How Excel Treats Disk Files.
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2019-05-19 12:36:14
Willy Vanhaelen
For • XLSB: "...instead of XLSX ..." should be "... instead of XLSM ..." since XLSB files can also contain macros.
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Please Note:
This article is written for users of the following Microsoft Excel versions: 2007, 2010, 2013, 2016, 2019, and Excel in Office 365. If you are using an earlier version (Excel 2003 or earlier), this tip may not work for you. For a version of this tip written specifically for earlier versions of Excel, click here: 
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